Sunday, 10 February 2008

animal experiments may be less useful



Animal experiments may be less useful than alternative methods

The way the argument about usefulness of animal experimentation for

medical purposes is put by its defenders is often fallacious for a

very simple reason: it is on qualitative, and not quantitative,

grounds.

(In addition, it goes against the nature of advanced science,

historically, to reason in qualitative and not quantitative terms. The

most developed sciences, like physics, and fields of science reach

their maturity by going from being qualitative to being quantitative,

especially in recent times.)

When people say `drug x was developed through animal experiments' or

`treatment y was found researching on animal models', the point is not

even whether what they say is true or not.

The relevant question is: how many (how many millions, more likely)

animals were used, how many experiments that had no useful result were

necessary before arriving at that particular single result?

It is a statistical problem that we should address.

Because, had we used a different method of research, the statistical

utility (I mean, for example, the percentage of successes) could have

been higher.

We must always use this yardstick, this criterion for comparison.

(This is the way that control groups are used in tests: I'm here

transferring a scientific technique to a meta-scientific context.)

It may very well turn out that, when compared with other methods

already in existence or that we know could be developed, the

percentage of successes in medical animal experimentation, among the

number of all experiments performed, is extremely low.

It could also turn out that the corresponding percentage of misleading

results (eg penicillin, or the role of smoking in lung cancer) or

downright deleterious effects is higher than it needs to be.

It's certainly well worth investigating along these lines, from now

on.

posted by Of Human and Non-Human Animals at 9:40 AM

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